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Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues.
APC 2; APC2; APO C2; Apo CII; APOC 2; ApoC II; Apoc2; APOC2 protein; ApoCII; APO-CII; apoC-II; Apolipoprotein C II; apolipoprotein C2; Apolipoprotein CII; Apolipoprotein C-II; ApolipoproteinCII; MGC75082; ProapoC-II; Proapolipoprotein C-II; RGD1560725
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